Pure Alpha Arbutin Powder 50gm

FACT SHEET:
CONCENTRATION OF ALPHA ARBUTIN: 99.96%

PERCENTAGE TO USE: 0.2-2%

CAS NO: 84380- 01-8

MOLECULAR FORMULA / MOLECULAR WEIGHT: C12H16O7 = 272.25

APPEARANCE: White to Almost white powder to crystal

SOLUBILITY: Soluble in water and ethanol. Alpha arbutin is a water-soluble ingredient, which means it dissolves readily in water. Therefore, water is the best solvent to use when formulating alpha arbutin. It has a solubility of approximately 1 g/10 mL of water at room temperature (25°C)

SOLUBILITY (SLIGHTLY SOL. IN): DMSO (Slightly), Methanol (Slightly)

SOLUBILITY (INSOLUBLE IN): insoluble in benzene, chloroform, carbon disulfide

STORAGE: 2-8°C Refrigerator

PKa: 10.10±0.15(Predicted)

pH (1% IN WATER): Ideal pH range 5-7. Alpha arbutin is most stable at a pH of 5.5-7.5, and it can start to degrade and lose its efficacy at pH levels below 5.5. Therefore, it is important to adjust the pH of the formulation appropriately to ensure the stability and effectiveness of alpha arbutin.

Solubility (1% in water): Clear, colorless solution

DISSOLVING TEMPERATURE: Add to formula at temperature <40°C (104°F)

TIME TO WORK: On average it will take 1-2 months of consistent topical use of Alpha arbutin before you begin to see improvements.

HOW TO CALCULATE 2% 100 ML ALPHA ARBUTIN :

CALCULATION FOR ALPHA ARBUTIN : 2 × 100 ÷ 100 = 2 GM

CALCULATION FOR DISTILLED WATER: 100-2 = 98 ML

It is important to note that Alpha arbutin should be dissolved slowly and gently to prevent degradation or decomposition. It is recommended to dissolve it with constant stirring and a low heat source to avoid overheating the solution. The recommended temperature range for dissolving Alpha arbutin is Less than 40°C (104°F)

ALPHA ARBUTIN FORMULATION GUIDE:
(for 100 ml serum )

Ingredients:
2% Alpha Arbutin (2gm)
89.5% Distilled Water (89.5 ml)
8% Glycerin (8 ml)
0.5% Preservative (e.g. Germall Plus) (0.5 ml)

Instructions:
In a clean and sterile container, combine distilled water and glycerin.

Mix well until glycerin is fully dissolved in the water.

Add alpha arbutin to the mixture and stir until fully dissolved.

Add the preservative to the mixture and mix well.

Store the final product in a clean, airtight container.

This formulation is suitable for a water-based serum or lotion. It is recommended to test the pH of the final product and adjust if necessary to ensure it falls within the appropriate range for skin application (usually around pH 4-6). It is also important to perform stability testing on the final product to ensure it remains stable over time.